CGB anticorps
Aperçu rapide pour CGB anticorps (ABIN7794910)
Antigène
Voir toutes CGB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Human HCG Beta (Clone 208)-Purified
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Specificité
- Mouse Anti-Human Chorionic Gonadotropin (HCG) Beta (Clone 208) recognizes Human Chorionic Gonadotropin (HCG) Beta. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Human chorionic gonadotropin (hCG) is a peptide hormone produced in pregnancy, that is made by the embryo soon after conception and later by the syncytiotrophoblast (part of the placenta). Its role is to prevent the disintegration of the corpus luteum of the ovary and thereby maintain progesterone production that is critical for a pregnancy in humans. hCG may have additional functions, for instance it is thought that it affects the immune tolerance of the pregnancy. Early pregnancy testing generally is based on the detection or measurement of hCG. hCG interacts with the LHCG receptor and promotes the maintenance of the corpus luteum during the beginning of pregnancy causing it to secrete the hormone progesterone. Progesterone enriches the uterus with a thick lining of blood vessels and capillaries so that it can sustain the growing fetus. Due to its highly negative charge hCG may repel the immune cells of the mother, protecting the fetus during the first trimester. It has also been suggested that hCG levels are linked to the severity of morning sickness in pregnant women. Because of its similarity to LH, hCG can also be used clinically to induce ovulation in the ovaries as well as testosterone production in the testes. As the most abundant biological source is women who are presently pregnant, some organizations collect urine from gravidae to extract hCG for use in fertility treatment.
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Immunogène
- Purified Recombinant Human Chorionic Gonadotropin (HCG) Beta (>98%)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Concentration
- 1 μg/mL
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Buffer
- This purified antibody is supplied in 0.01 M phosphate buffered saline (PBS), pH 7.4, containing 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For long term storage freeze working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
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- CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))
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Autre désignation
- Chorionic Gonadotropin Beta
Antigène
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